The HIV Modelling Consortium
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چکیده
■ Identifying questions that demand mathematical modelling input and identifying new modelling results that may require further validation. ■ Facilitating sharing of information, modelling techniques, data and expertise between research groups. ■ Providing a forum for rigorous review of new mathematical modelling research and tools. ■ Providing funding through sub-contracts to commission research to address those needs.
منابع مشابه
How can mathematical models advance tuberculosis control in high HIV prevalence settings?
Existing approaches to tuberculosis (TB) control have been no more than partially successful in areas with high human immunodeficiency virus (HIV) prevalence. In the context of increasingly constrained resources, mathematical modelling can augment understanding and support policy for implementing those strategies that are most likely to bring public health and economic benefits. In this paper, ...
متن کاملHIV, TB and ART: the CD4 enigma
1 This is a development of a presentation given by Brian Williams at the ‘Modelling and Quantitative Research Priorities’ meeting of the TB Modelling and Analysis Consortium (TB MAC), funded by the Bill and Melinda Gates Foundation, 28th and 29th September 2012, Johannesburg, South Africa Abstract The concentration of CD4+ T-lymphocytes (CD4 count) in a person’s plasma is widely used to decide ...
متن کاملHIV Treatment as Prevention: Models, Data, and Questions—Towards Evidence-Based Decision-Making
Antiretroviral therapy (ART) for those infected with HIV can prevent onward transmission of infection, but biological efficacy alone is not enough to guide policy decisions about the role of ART in reducing HIV incidence. Epidemiology, economics, demography, statistics, biology, and mathematical modelling will be central in framing key decisions in the optimal use of ART. PLoS Medicine, with th...
متن کاملApplication of Genetic Algorithms for Pixel Selection in MIA-QSAR Studies on Anti-HIV HEPT Analogues for New Design Derivatives
Quantitative structure-activity relationship (QSAR) analysis has been carried out with a series of 107 anti-HIV HEPT compounds with antiviral activity, which was performed by chemometrics methods. Bi-dimensional images were used to calculate some pixels and multivariate image analysis was applied to QSAR modelling of the anti-HIV potential of HEPT analogues by means of multivariate calibration,...
متن کاملAn Efficient Method to Solve the Mathematical Model of HIV Infection for CD8+ T-Cells
In this paper, the mathematical model of HIV infection for CD8+ T-cells is illustrated. The homotopy analysis method and the Laplace transformations are combined for solving this model. Also, the convergence theorem is proved to demonstrate the abilities of presented method for solving non-linear mathematical models. The numerical results for $N=5, 10$ are presented. Several $hbar$-c...
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